Bone & Joint Research Activities

Ongoing Projects:

1. Clinical trial evaluation of the association between gut microbiota and joint prosthesis infection: a systematic review and meta-analysis. (2023-ongoing) 

 

2. Comparison between clinical outcome of the meniscal repairing by CMI, Actifit, NUsurface as commercial artificial meniscus: systematic review (2023- ongoing) 

 

3. The effect of IV and local tranexamic acid on surgeon visualization, clinical outcomes, and blood loss, on pump pressure during arthroscopic rotator cuff repair: a randomized clinical trial (2023- ongoing) 

 

4. Clinical efficacy and safety of Mesenchymal stem cells in treatment of osteogenesis imperfect: A systematic review and meta-analys (2023- ongoing) 

 

5. Fabrication and structural, mechanical, and biological characterization of composite scaffolds based on hyaluronic acid for meniscus repairing application (2023- ongoing) 

 

6. Fabrication and Characterization of micro-nano composite electrospun nanofibers of PU/PCL hand arteries implantation (2023- ongoing) 

 

7. Developing of PHEMA-gelatin scaffold enriched with graphene oxide, bioactive glass and leaf extracts (Rosmarinus officinalis) for the regeneration of rabbit mandibular defect (2023- ongoing) 

 

8. Synthesis of acrylic bone cement functionalized with nanoparticles to improve mechanical properties and biological performance, especially for local therapeutic delivery to spinal metastases (2023- ongoing) 

 

9. Clinical evaluation of the relationship between Prosthesis Joint Infection and gut microbiota disturbance in an animal model (2023- ongoing) 

 

10. Structural, mechanical and in vitro properties evaluation of composite scaffolds base on alginate and loaded-tobramycin bioglass contain induced osteogenic differentiation for bone tissue engineering applications : preclinical phase (2023- ongoing) 

 

11. Evaluation of the clinical performance of 3D printed scaffolds based on alginate and bio glass nanoparticles containing magnesium and strontium in inducing the differentiation of mesenchymal stem cells towards osteoblast cells with the aim of treating non-union fractures in animal study (2023- ongoing) 

 

12. Clinical outcome of massive rotator cuff repair, clinical and radiological follow-up (2022-ongoing) 

 

 

13. A Comparison between biomechanical function of Flexor Sheath Artificial Pulley and Natural Pulleys: A Cadaver study (2022-ongoing) 

 

14. Evaluation of the efficiency of thymoquinone-incorporated collagen-nanohydroxyapatite scaffold in induction of mesenchymal stem cells differentiation into bone cells for bone tissue engineering (2021-ongoing) 

 

15. Development of microvascular graft for hand digital arteries by electrospinning (2020- ongoing) 

 

16. Development of a mesh suture with controlled drug release for tendon fixation (2017- ongoing) 

Completed Projects:

1. Evaluating the efficacy of 3D printing of collagen scaffolds incorporating with crocin for bone regeneration (2018- 2022) 

 

2. Antimicrobial effects of modified HA/Ag composite coating on external fixator pins: An in vitro/in vivo study (2018-2022) 

Contact Us

Orthopedics Research Center was founded in 2008, Mashhad, Iran, with the principal purpose of advancing scientific and clinical research in orthopedics and traumatology.
Ahmad-Abad St. Ghaem Hospital, Mashhad, 91766-99199, Iran
Tell: +98 51 3801 2638
Fax: +98 51 3841 7453
Email: orthopedics.research.center@gmail.com, ORC@mums.ac.ir